TY - JOUR T1 - Anti-emtic effect of Trachyspermum ammi L. fruit extracts in young chickens TT - بررسی اثرات ضد تهوعی عصارههای آبی و الکلی زنیان در جوجه مرغ JF - jmpir JO - jmpir VL - 3 IS - 9 UR - http://jmp.ir/article-1-751-en.html Y1 - 2004 SP - 15 EP - 22 KW - Trachyspermum ammi fruit KW - Anti-emetic KW - Young chickens KW - Copper sulfate KW - Ipecac N2 - The anti-emetic effect of the aqueous and ethanolic extracts of Trachyspermum ammi fruit was studied in young chickens. Emesis was induced in the chickens using copper sulfate (60 mg/kg, orally) and ipecac (600 mg/kg, orally). The LD50 values of the aqueous and ethanolic extracts (i.p.) were 2753 mg/kg and 747 mg/kg in the chickens, respectively. The aqueous extract (800-2000 mg/kg, i.p.) and ethanolic extract (40-100 mg/kg, i.p.) significantly prevented the emesis induced by copper sulfate and ipecac. These results indicate that the extracts of T. ammi fruit extracts have an anti-emetic activity in young chickens with peripheral and central mechanisms. M3 ER -