Eidi A,  Eidi M,  Oryan S,  Fallahyan F,  Darzi Darounkala R. Hypoglycaemic effect of alcoholic extract of olive (
Olea europaea L.) leaf in healthy and diabetic rats.  J. Med. Plants 2004; 3 (12) :36-40
URL: 
http://jmp.ir/article-1-726-en.html     
                     
                    
                    
                    
					 
					
                 
                
                    
                    
                    
                    1- Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran , akram_eidi@yahoo.com
 2- Biology Department, Science Faculty, Varamin Unit, Islamic Azad University, Tehran, Iran 
 3- Biology Department, Science Faculty, Teacher Training University, Tehran, Iran 
 4- Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran 
                    
                    
                    Abstract:       (7037 Views)
                    
                    
                    In traditional medicine leaves of olive (Olea europaea L.) are used as a diuretic, hypotensive, antibacterial and antiatherosclerotic. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of leaves of olive for 14 days on the level of glucose and insulin in healthy and streptozotocin-induced diabetic rats were evaluated. The results showed that oral administration of the alcoholic extract of olive exhibited a significant reduction in blood glucose and increased plasma insulin in diabetic rats. The extract didnot change the level of blood glucose and plasma insulin in healthy rats significantly. A comparison was made between the action of the alcoholic extract and a known antidiabetic drug, glibenclamide (600 g/kg body wt.). The hypoglycaemic effect of the extract was greater than that observed with glibenclamide.
                     
                    
                    
                    
                    
                    Type of Study:  
Research |
                    Subject: 
                    
Pharmacology & Toxicology  Received: 2004/03/13 | Accepted: 2004/11/1 | Published: 2004/12/15