سال 9، شماره 35 - ( English 1389 )                   سال 9 شماره 35 صفحات 93-98 | برگشت به فهرست نسخه ها

XML English Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Zahedi A, Khaki A, Ahmadi-Ashtiani H, Rastegar H, Rezazadeh S. Zingiber officinale Protective Effects on Gentamicin’s Toxicity on Sperm in Rats. J. Med. Plants. 2010; 9 (35) :93-98
URL: http://jmp.ir/article-1-271-fa.html
Zahedi A، Khaki A، Ahmadi-Ashtiani HR، Rastegar H، Rezazadeh Sh. Zingiber officinale Protective Effects on Gentamicin’s Toxicity on Sperm in Rats. فصلنامه گياهان دارویی. 1389; 9 (35) :93-98

URL: http://jmp.ir/article-1-271-fa.html


1- Faculty of Veterinary Medicine, Islamic Azad University, Rasht Branch
2- Faculty of Veterinary Medicine, Islamic Azad University, Tabriz Branch ، arashkhaki@yahoo.com
3- Biochemistry and Nutrition Department of Zanjan University of Medical Sciences, Zanjan, Iran & Department of Clinical Biochemistry, School of Medical Science, Tarbiat-e-Modarres University
4- Ministry of Health and Medical Education, Food & Drug Laboratory Research Center
5- Institute of Medicinal Plants, ACECR
چکیده:   (3793 مشاهده)
Background: Ginger rhizome (Zingiber officinale R., family: Zingiberaceae) is used medicinally and as a culinary spice and has anti-oxidant and cell-protective effects in animals and humans body. Objective: The aim of this study was to investigate the influence of Ginger rhizome toxicity of Gentamicin on sperm parameters in male rats. Methods: Forty Wistar male rat (n=40) were allocated into four groups, control (n=10) and test groups (n=30), that subdivided into groups of 3 that received ginger rhizome powder (100 mg/kg/day), gentamicin group that received, 5 mg/kg/day and ginger group that received, 5 mg/kg/day gentamicin additionally, for 30 consequence day. Animals were kept in standard conditions. In thirty day the testes tissue of Rats in whole groups were collected. Results: Ginger administration caused a marked increase in the testosterone concentrations of the rats even in spite of receiving 5 mg/kg/day gentamicin in compared with the control and gentamicin treated groups. Conclusion: Ginger rhizome is able to overcome reproductive toxicity of gentamicin and induces spermatogenesis probably mainly through the elevation of testosterone levels.
واژه‌های کلیدی: Ginger rhizome، Male fertility، Testosterone، Toxicity
متن کامل [PDF 164 kb]   (2003 دریافت)    
نوع مطالعه: پژوهشی | موضوع مقاله: فارماكولوژی و سم شناسی
دریافت: 1389/4/1 | پذیرش: 1389/6/17 | انتشار: 1389/8/7

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
CAPTCHA

ارسال پیام به نویسنده مسئول


بازنشر اطلاعات
Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.

کلیه حقوق این وب سایت متعلق به فصلنامه علمی پژوهشی گیاهان دارویی می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2021 CC BY-NC 4.0 | Journal of Medicinal Plants

Designed & Developed by : Yektaweb