year 18, Issue 72 (11-2019)                   J. Med. Plants 2019, 18(72): 98-106 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Pakniat H, Hajiseyed Javadi E, Golmohammadi Z, Ashrafi M. The Effect of Ginger on Primary Dysmenorrhea in Students of Qazvin University of Medical Sciences. J. Med. Plants 2019; 18 (72) :98-106
URL: http://jmp.ir/article-1-2705-en.html
1- Department of Obstetrics and Gynecology, Faculty of Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
2- Department of Obstetrics and Gynecology, Faculty of Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran , dr_seidjavadi@yahoo.com
3- Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
Abstract:   (4393 Views)
Background: Dysmenorrhea is a major individual and public health problem in women. Recently, according to the high prevalence of dysmenorrhea, different medical treatments including herbal medicines have been used.
Objective: The aim of this study is to evaluate the effect of ginger on dysmenorrhea severity in students in Qazvin University of Medical Science, Iran.
Methods: In this randomized clinical trial, 100 female students aged 18 to 25 years with moderate to severe dysmenorrhea were included. The participants were allocated to two groups of control and intervention by randomization. The intervention group were received 500 mg of ginger tablet and 250 mg of Mefenamic Acid capsule twice a day and the control group took placebo and Mefenamic Acid 250 mg capsule two times a day from two days before and within the first three days of the onset of the Menstrual period. Pain intensity were measured with VAS tool before and two months after the prescription of drugs.
Results: The results of our study showed the pain intensity after the intervention in the first month, was significantly less than the control group (3.72 vs 5.44) (P<0.001) and in the second month, the pain in intervention group was significantly less than the control group (3.2 vs5.2) (P<0.001), and no complications were observed in the intervention group.
Conclusion: The result of this study indicated that herbal medicine like ginger has a great effect on reduction of dysmenorrhea severity and furthermore studies are suggested to perform in order to find a suitable dose of ginger for complete treatment of dysmenorrhea and other menstrual symptoms.
Keywords: Dysmenorrhea, Ginger, Pain
Full-Text [PDF 670 kb]   (1342 Downloads)    
Type of Study: Research | Subject: Pharmacology & Toxicology
Received: 2018/01/24 | Accepted: 2018/08/9 | Published: 2019/10/28

References
1. Fritz MA and Speroff L. Clinical gynecologic endocrinology and infertility. 8th ed. lippincott Williams & wilkins. Philadelphia. 2011, pp: 579.
2. Burkman RT. Berek & Novak's gynecology. JAMA. 2012; 308 (5): 516-7. [DOI:10.1001/jama.308.5.516]
3. Iacovides S, Avidon I and Baker FC. What we know about primary dysmenorrhea today: a critical review. Human Reproduction Update 2015; 21 (6): 762-78. [DOI:10.1093/humupd/dmv039]
4. Eden J. Dysmenorrhoea and premenstrual syndrome. Essentials of Obstetrics and Gynaecology. 1998, pp: 332-7.
5. Nayeban S, Jafarnejad F, Nayeban S and Sefidgaran A. A Comparison of the Effects of Vitamin E and Vitamin B1 on the Severity and Duration of Pain in Primary Dysmenorrhea. J. Midwifery and Reproductive Health 2014; 2 (2): 143-6.
6. Akhlaghi F, Zyrak N, Nazemian S. Effect of vitamin E on primary dysmenorrhea. Journal of hayat. 2009; 15 (1): 13-9.
7. Davis AR and Westhoff CL. Primary dysmenorrhea in adolescent girls and treatment with oral contraceptives. J. Pediatric and Adolescent Gynecol. 2001; 14 (1): 3-8. [DOI:10.1016/S1083-3188(00)00076-0]
8. Sanfilippo J and Erb T. Evaluation and management of dysmenorrhea in adolescents. Clinical Obstetrics and Gynecol. 2008; 51 (2): 257-67. [DOI:10.1097/GRF.0b013e31816d2307]
9. Eccles R, Holbrook A and Jawad M. A double-blind, randomised, crossover study of two doses of a single-tablet combination of ibuprofen/paracetamol and placebo for primary dysmenorrhoea. Current Medical Research and Opinion 2010; 26 (11): 2689-99. [DOI:10.1185/03007995.2010.525028]
10. Kalish GM, Patel MD, Gunn ML and Dubinsky TJ. Computed tomographic and magnetic resonance features of gynecologic abnormalities in women presenting with acute or chronic abdominal pain. Ultrasound Q. 2007; 23 (3): 167-75. [DOI:10.1097/RUQ.0b013e31815202df]
11. Kamaya A, Shin L, Chen B and Desser TS. Emergency gynecologic imaging. Semin Ultrasound CT MRI. 2008; 29 (5): 353-68. [DOI:10.1053/j.sult.2008.06.006]
12. Fritz MA and Speroff L. Female infertility. Clinical gynecologic endocrinology and infertility. 2011, pp: 1162-3.
13. Ryan JL, Heckler CE, Roscoe JA, Dakhil SR, Kirshner J, Flynn PJ and et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Supportive Care in Cancer 2012; 20 (7): 1479-89. [DOI:10.1007/s00520-011-1236-3]
14. Kiuchi F, Iwakami S, Shibuya M, Hanaoka F and Sankawa U. Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chemical and Pharmaceutical Bulletin 1992; 40 (2): 387-91. [DOI:10.1248/cpb.40.387]
15. Ozgoli G, Goli M and Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. The Journal of Alternative and Complementary Medicine 2009; 15 (2): 129-32. [DOI:10.1089/acm.2008.0311]
16. Rahnama P, Fallah Huseini H, Mohammadi H, Modares M, Khajavi Shojaee K, Askari M and et al. The effects of Zingiber officinal R. On primary dysmenorrhea. Journal of Medicinal Plants 2010; 4 (36): 81-6.
17. Torshiz M, Golmakani N, Saadatjoo S and Rakhshandeh H. Zintoma (Ginger)in the treatment of pri may dysmenorrheal. Modern Care Journal (Scientific Quarterly of Birjand Nursing & Midwifery Faculty). 2005; 2 (3): 5-8.
18. Shirvani MA, Motahari-Tabari N and Alipour A. The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial. Archives of Gynecology and Obstetrics 2015; 291 (6): 1277-81. [DOI:10.1007/s00404-014-3548-2]
19. Rahnama P, Montazeri A, Huseini HF, Kianbakht S and Naseri M. Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC Complementary and Alternative Medicine 2012; 12 (1): 92. [DOI:10.1186/1472-6882-12-92]
20. Kashefi F, Khajehei M, Tabatabaeichehr M, Alavinia M and Asili J. Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial. Pain Management Nursing 2014; 15 (4): 826-33. [DOI:10.1016/j.pmn.2013.09.001]
21. Grzanna R, Lindmark L and Frondoza CG. Ginger-an herbal medicinal product with broad anti-inflammatory actions. J. Medicinal Food 2005; 8 (2): 125-32. [DOI:10.1089/jmf.2005.8.125]
22. Davdabady Farahani M and Seyyedzadeh Aghdam N. Comparison of ginger and valerian on the severity of primary dysmenorrhea: a randomized triple blind clinical trial. Complementary Medicine Journal of faculty of Nursing & Midwifery 2013; 3 (2): 494-503.
23. Samadi N, Amani F, Naghizadeh M, Alahiari I, GHezelbash S and Kazemzadeh R. Effect of Using Combination of Fennel, Chamomile and Ginger on Relieving Symptoms of Primary Dysmenorrheal among Students in Ardabil University of Medical Sciences in 2012. SJIMU. 2015; 22 (6): 159-64.
24. Shirooye P, Hashem-Dabaghian F, Hamzeloo-Moghadam M, Afrakhteh M, Bioos S and Mokaberinejad R. A clinical comparative study of oral and topical ginger on severity and duration of primary dysmenorrhea. Research J. Pharmacognosy 2017; 4 (1): 23-32.
25. Kavuluru VP. A study to assess the effectiveness of ginger preparation on dysmenorrhea among adolescent girls. IJAR. 2017; 3 (3): 22-5.
26. Singh P, Nageshwar V and Krishnaveni R. A Study to Assess the Effectiveness of Ginger Remedy in Reduction of Dysmenorrhea among Adolescent Girls. Indian Journal of Public Health Research & Development 2017; 8 (2): 197-200. [DOI:10.5958/0976-5506.2017.00110.3]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Medicinal Plants

Designed & Developed by : Yektaweb