year 18, Issue 72 (11-2019)                   J. Med. Plants 2019, 18(72): 66-80 | Back to browse issues page


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Babaei-Abandansari S, Bagheri-Nesami M, Gholipour-Baradari A, Yazdani-cherati J, Yosefi S. The Prophylactic Effect of Cuminum cyminum Extract on Gastric Residual Volume in Traumatic Patients under Ventilator Hospitalized in Intensive Care Unit. J. Med. Plants 2019; 18 (72) :66-80
URL: http://jmp.ir/article-1-2703-en.html
1- Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran
2- Traditional and Complementary Medicine Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran , anna3043@gmail.com
3- Department of Anesthesiology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
4- Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran
5- Department of Traditional Persian Medicine, Traditional and Complementary Medicine, Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
Abstract:   (4393 Views)
Background: Increased Gastric residual volume (GRV) is one of the common problems in ICU.
Objective: The aim of this study was to determine the effect of cumin extract on gastric residual volume in patients with traumatic episodes hospitalized in ICU.
Method: This double-blind randomized clinical trial was conducted on 60 patients traumatic hospitalized in ICU. Patients were randomly assigned to one of two groups: cumin (n = 30) and distilled water (n = 30). In the intervention group, 6 grams of cumin extract in 3 divided doses were given 50 drops in 30 cc of urban water at 3 times every 8 hours after. The remaining volume was recorded for up to 4 consecutive days and the data were compared in two groups. (IRCT: 201610297494N24).
Results: Before the intervention, there was no significant difference between the mean GRV in the cumin group and placebo group (P = 0.63). Comparing the two groups of placebo and placebo, there was no significant difference in the amount of residual stomach in hospitalized patients with ICU on the first day (P = 0.13), but on the second, third and fourth days, this difference was significant between the two groups (p = 0.001).Comparing the two groups of intervention and placebo, the average volume of residual stomach before and during 4 consecutive days after intervention was significant (P = 0.001).
Conclusion: The results of this study showed that cumin extract was effective in decreasing residual stomach volume in hospitalized patients with ICU in comparison with placebo.
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Type of Study: Research | Subject: Pharmacology & Toxicology
Received: 2018/05/13 | Accepted: 2018/07/28 | Published: 2019/10/28

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