سال 9، شماره 35 - ( English 1389 )                   سال 9 شماره 35 صفحات 88-92 | برگشت به فهرست نسخه ها

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1- Department of Microbiology, Food and Drug Laboratory Research Center (FDLRC), MOH & ME
2- Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences ، Hajimehd@tums.ac.ir
3- Department of Biotechnology, Pasture Institute of Iran
4- Molecular Biotechnology Research Center, Baqiatalah University of Medical Sciences
5- Department of Microbiology, Pharmaceutical Sciences Branch, Islamic Azad University
6- Department of Pharmacognosy and Pharmaceutics, Institute of Medicinal Plants, ACECR
چکیده:   (4115 مشاهده)
Background: Mentha species are widely used in traditional medicine mostly as anti-flatulence. Nowadays, their usage as flavor and preservative in food, cosmetic and pharmaceutical industries has been developed. Moreover, cytotoxic effects of some Mentha species have been reported. Objective: In this study, cytotoxic properties of Mentha piperita, M. spicata, M. aquatica, M. crispa, M. pulegium and M. longifolia have been investigated. Methods: Different concentrations of essential oils and total extracts of six Mentha species were tested by MTT assay against Vero, Hep2 and Hela cell lines. Results: The results showed that all samples were toxic against Vero, Hela and Hep2 cell lines (IC50 28.1-166.2 µg/ml). Conclusion: All examined Mentha species extracts and essential oils have cytotoxic effects but some of them could be considered as potent toxic agents.
واژه‌های کلیدی: Mentha، Cytotoxic effects، MTT، Vero، Hela، Hep2 cell line
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نوع مطالعه: پژوهشی | موضوع مقاله: فارماكوگنوزی و فارماسيوتيكس
دریافت: 1389/3/14 | پذیرش: 1389/6/6 | انتشار: 1389/8/7

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