year 19, Issue 74 (6-2020)                   J. Med. Plants 2020, 19(74): 84-107 | Back to browse issues page

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Beladi M, Akhavansepahy A, Mehrabian S, Esmaili A, Sharifnia F. Evaluation of antimicrobial role of nanocapsules containing Cornus mass extract synthesized by emulsion method on antibiotic resistant bacteria. J. Med. Plants 2020; 19 (74) :84-107
URL: http://jmp.ir/article-1-2004-en.html
Evaluation of antimicrobial role of nanocapsules containing Cornus mass extract synthesized by emulsion method on antibiotic resistant bacteria
Maryam Beladi1 , Abbas Akhavansepahy * 2, Sedigeh Mehrabian1 , Akbar Esmaili3 , Fariba Sharifnia1
1- Faculty of Biology, Islamic Azad University, Tehran North Branch, Tehran, Iran
2- Faculty of Biology, Islamic Azad University, Tehran North Branch, Tehran, Iran , akhavansepahy@gmail.com
3- Faculty of Chemical Engineering, Islamic Azad University, Tehran North Branch, PO Box 19585/936, Tehran, Iran
Abstract:   (2664 Views)
Background: Due to the increase in the strains of antibiotic-resistant bacteria, it is necessary to obtain effective herbal compounds and nanocapsules synthesized from plant extracts to eliminate these strains. Objective: The present research study was conducted to examine the antibacterial effects of Cornus mass extract and its synthesized nano-capsules on the bacterial strains resistant to antibiotics. Methods: Samples including a combination of (urine, sputum, wounds and blood) of 436 hospitalized patients was collected and a number of 50 strains which demonstrated the highest resistance to antibiotics was separated to examine the antibacterial characteristics of the innovative compositions under study. Results: The findings showed that from among the 50 strains under study in 80% of the cases the E. coli bacteria and in 20% of the cases the Acinetobacter were the cause of infections. with the increase in the concentration of the extract, the size and dimension of nano-capsules increased so much so that in a concentration of 2.5 mg of extract, nano-particles as large as 72 nanometers was reported. Also, in fixed concentration of extracts diluted in more aceton, the size and dimension of nano-particles decreased to the extent that in a concentration using 15 mililitre of aceton, nano-particles equal to 66 nano meter was observed. Conclution: The findings relating to the antimicrobial characteristics of the Cornus mass extracts and its synthesized nano-capsules showed that respectively 36% and 56% of the strains under study possess antibacterial characteristics.
Keywords: Cornus mass, Antibiotical resistance, Antimicrobial, Nano capsules
Full-Text [PDF 1147 kb]   (1183 Downloads)    
Type of Study: Research | Subject: Medicinal Plants
Received: 2018/01/18 | Accepted: 2018/12/9 | Published: 2020/07/21
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