Journal of Medicinal Plants

en Essential oil Composition and Antioxidant Activity of Levisticum officinale Koch. at Various Phenological Stages Essential oil composition and antioxidant activity of Levisticum officinale Koch. at various phenological stages فارماكوگنوزی و فارماسيوتيكس Pharmacognosy & Pharmaceutics پژوهشی Research Background: The leaves, roots and seeds of Lovage (Levisticum officinale Koch) being used as an herb, vegetable and spice. Objective: The aim of this study is evaluation of the changes of phytochemical compound in aerial parts of the Lovage plants at different developmental stages as well as antioxidant activity. Methods: The plants were harvested from Hezar Mountain. After drying, essential oils were extracted by steam distillation. To identify the essential components GC and GC-MS was used. Antioxidant activity of samples was examined by diphenylpicrylhydrazyl (DPPH) assay. Results: The average yield of essential oil was respectively, 2.3% and 3.1% and 1.5% respectively, in vegetative, Flowering and seed stage. The oil analysis results showed that 21 compounds were identified in the vegetative stage. β-phellandrene (10.7%) and α-Terpinyl acetate (% 38.9) and Curzerene (% 10.6) were the major compound. in the reproductive stage, 22 compounds were identified including β-phellandrene (20.3%) and α-Terpinyl acetate (% 20.4) and γ-Cadinene (12.1%). in the seed stage β-phellandrene (21.1%) and α-Terpinyl acetate (% 25.3) and Sabinene (10.2%) were the highest. Analysis of variance showed that the effect of harvesting time has significant effect on plant height, stem branch number and yield of oil. The Higher antioxidant power was observed respectively in the flowering stage (83%), vegetative stage (68%) and seed stage (60%). Conclusion: The phytochemical and antioxidant compounds in Levisticum officinale depend on the phenological stage. Background: The leaves, roots and seeds of Lovage (Levisticum officinale Koch) being used as an herb, vegetable and spice. Objective: The aim of this study is evaluation of the changes of phytochemical compound in aerial parts of the Lovage plants at different developmental stages as well as antioxidant activity. Methods: The plants were harvested from Hezar Mountain. After drying, essential oils were extracted by steam distillation. To identify the essential components GC and GC-MS was used. Antioxidant activity of samples was examined by diphenylpicrylhydrazyl (DPPH) assay. Results: The average yield of essential oil was respectively, 2.3% and 3.1% and 1.5% respectively, in vegetative, Flowering and seed stage. The oil analysis results showed that 21 compounds were identified in the vegetative stage. β-phellandrene (10.7%) and α-Terpinyl acetate (% 38.9) and Curzerene (% 10.6) were the major compound. in the reproductive stage, 22 compounds were identified including β-phellandrene (20.3%) and α-Terpinyl acetate (% 20.4) and γ-Cadinene (12.1%). in the seed stage β-phellandrene (21.1%) and α-Terpinyl acetate (% 25.3) and Sabinene (10.2%) were the highest. Analysis of variance showed that the effect of harvesting time has significant effect on plant height, stem branch number and yield of oil. The Higher antioxidant power was observed respectively in the flowering stage (83%), vegetative stage (68%) and seed stage (60%). Conclusion: The phytochemical and antioxidant compounds in Levisticum officinale depend on the phenological stage. Lovage (Levisticum officinale Koch.), Essential oils, Antioxidant activity, vegetative stage, flowering stage, seed stage Lovage (Levisticum officinale Koch.), Essential oils, Antioxidant activity, vegetative stage, flowering stage, seed stage 45 55 http://jmp.ir/browse.php?a_code=A-10-1200-1&slc_lang=en&sid=1 Neda Mohamadi ندا محمدی mohamadineda15@gmail.com 100319475328460041388 100319475328460041388 No Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran Peyman Rajaei پیمان رجایی rajaeipeyman@gmail.com 100319475328460041389 100319475328460041389 Yes Departments of Biology, Kerman Branch, Islamic Azad University, Kerman, Iran Departments of Biology, Kerman Branch, Islamic Azad University, Kerman, Iran Mehran Moradalizadeh مهران مرادعلی زاده mo_mehran@yahoo.com 100319475328460041390 100319475328460041390 No Departments of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran Departments of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran Mohammad Sadegh Amiri محمدصادق امیری M.S._Amiri@pnu.ac.ir 100319475328460041391 100319475328460041391 No Payame Noor University, Tehran Department of Biology, Payame Noor University, Tehran, Iran