TY - JOUR JF - jmpir JO - J. Med. Plants VL - 9 IS - 34 PY - 2010 Y1 - 2010/5/01 TI - Antinociceptive and Anti-inflammatory Effects of Hydroalchoholic Extract of Anethum graveolens L. seed TT - بررسی اثرات ضد‌التهابی و ضددردی عصاره هیدروالکلی دانه گیاه Anethum graveolens L. N2 - Background: There are many reports about anti-inflammatory effect of Anethum graveolens L.(A.g) in Iranian traditional medicine. In current decade, based on using of neutriceuticales for healing, the use of herbal drugs became very common. Objective: In this study, regarding the mentioned purposes, we have evaluated anti-inflammatory and antinociceptive effects of Hydroalchoholic Extract of A.g seeds. Methods: In this research, male mice were used and in inflammatory test they were divided to 6 groups: control, dexamethasone (15 mg/kg), seed A.g. extract (100,200, 400,500mg/kg). All of the drugs were administered intraperitonally. The inflammation was caused by xylene-induced ear oedema. In order to evaluate the antinocicetive of Anethum graveolens L. seed, we used formalin test. Mice were divided to 6 groups: control, seed A.g. extract (100,200, 400, 500 mg/kg). All of drugs were administered intraperitonally. Results: The results indicated that A.g. extract has anti-inflammatory and antinociceptive effects. Conclusion: This study suggests A.g extract as a candidate for pain relieving for further studies. SP - 124 EP - 130 AU - Valadi, A AU - Nasri, S AU - Abbasi, N AU - Amin, GR AD - Department of Biology, Faculty of Science, PayamNoor University of Tehran KW - < KW - i> KW - Anethum graveolens< KW - /i> KW - L. seed KW - Inflammation KW - Nociception KW - Xylene-induced ear oedema KW - Formalin test UR - http://jmp.ir/article-1-293-en.html ER -