:: Volume 2, Issue 46 (6-2013) ::
J. Med. Plants 2013, 2(46): 1-12 Back to browse issues page
A Review on Medicinal Plant of Glycyrrhiza glabra L.
M Khanahmadi M1, H Naghdi Badi2, S Akhondzadeh3, F Khalighi – Sigaroodi1, A Mehrafarin2, S Shahriari4, R Hajiaghaee *1
1- 1- Pharmacognosy & Pharmaceutics Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR
2- 2- Cultivation & Development Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR
3- 3- Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences
4- 4- Department of Chemistry, ACECR, Kermanshah Branch, Kermanshah, Iran * Corresponding author: Institute of Medicinal Plants, ACECR
Abstract:   (8933 Views)
Glycyrrhiza glabra L (Licorice) as native and pasture medicinal plant has most important export rule. Glycyrrhizic acid (GA) or Glycyrrhizin as a main active component of licorice root and rhizomes, is a triterpenoid saponin claimed to be up to 30-50 times sweeter than sucrose and to be used in pharmaceuticals, food and tobacco industry. Licorice root is a traditional medicine used mainly for the treatment of peptic ulcer, hepatitis C, and pulmonary and skin diseases, although clinical and experimental studies suggest that it has several other useful pharmacological properties such as antiinflammatory, antiviral, antimicrobial, antioxidative, anticancer activities, immunomodulatory, hepatoprotective and cardioprotective effects. A large number of components have been isolated from licorice, including triterpene saponins, flavonoids, isoflavonoids and chalcones, with glycyrrhizic acid normally being considered to be the main biologically active component. Understanding of the limitations and challenges in the medicinal plant are need for planning principles for development activities and conservation in this field.In this review summarizes the phytochemical, pharmacological and pharmacokinetics data, together with the clinical as one of the most important herbs in exports and adverse effects of licorice.
Keywords: Glycyrrhiza glabra, Glycyrrhizic acid, Glycyrrhizin, Pharmacological effects
Full-Text [PDF 236 kb]   (5837 Downloads)    
Type of Study: Review | Subject: Pharmacognosy
Received: 2014/10/1 | Accepted: 2014/10/1 | Published: 2014/10/1

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Volume 2, Issue 46 (6-2013) Back to browse issues page