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:: دوره 1، شماره 33 و S 6 - ( ويژه نامه شماره 6 (به زبان انگليسي) 1388 ) ::
جلد 1 شماره 33 و S 6 صفحات 124-130 برگشت به فهرست نسخه ها
Effects of Sub-inhibitory Concentrations of Essential Oils of Mentha spicata and Cumminum cyminum on Virulence Factors of Pseudomonas aeruginosa
چکیده:   (2649 مشاهده)

  Background : Pseudomonas aeruginosa is one of important opportunistic pathogen, that cases serious infections . It produces many virulence factors, and this bacterium usually is resistance against antimicrobial agents.

  Objective :The aim of this study was evaluate the effects of sub-MICs of essential oils of Mentha spicata and Cumminum cyminum on alginate production, biofilm formation, swimming, twitching and adhesion in P. aeruginosa 8821M.

  Method : Minimal inhibitory concentrations (MIC) of essential oils of Mentha spicata and Cumminum cyminum were determined by macrodilution method. Alginate production, biofilm formation, swimming, twitching and adhesion in the present of sub-MICs (1/2, 1/4 and 1/8 MIC) of essential oils were determined in mucoid P. aeruginosa 8821M and compared with controls.

  Results : The MICs of essential oils against P. aeruginosa for M. spicata and C. cyminum oils were obtained 16 and 32 μg/ml respectively. The results show that all oils at 1/2 and 1/4 MICs were significantly reduced all tested virulence factors. At 1/8 MICs, M. spicata had effect just on adhesion but C. cyminum had effect on Alginate production, biofilm formation, swimming and twitching .

Conclusion : This study showed that sub-MIC levels of M. spicata and C. cyminum essential oils affected alginate production, biofilm formation, swimming, twitching and adhesion in
P. aeruginosa
8821M and it is probable to use of these medicinal plants for treating.
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نوع مطالعه: پژوهشي | موضوع مقاله: ميكروبيولوژي
دریافت: ۱۳۹۳/۹/۱ | پذیرش: ۱۳۹۳/۹/۱ | انتشار: ۱۳۹۳/۹/۱
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Mousavi Nadoshan S, Owlia P, Moein Najafabadi L, Rasooli I, Saderi H, Salari M. Effects of Sub-inhibitory Concentrations of Essential Oils of Mentha spicata and Cumminum cyminum on Virulence Factors of Pseudomonas aeruginosa. JMP. 2010; 1 (33) :124-130
URL: http://jmp.ir/article-1-524-fa.html

Effects of Sub-inhibitory Concentrations of Essential Oils of Mentha spicata and Cumminum cyminum on Virulence Factors of Pseudomonas aeruginosa. فصلنامه گياهان دارويي. 1388; 1 (33) :124-130

URL: http://jmp.ir/article-1-524-fa.html



دوره 1، شماره 33 و S 6 - ( ويژه نامه شماره 6 (به زبان انگليسي) 1388 ) برگشت به فهرست نسخه ها
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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