[صفحه اصلی ]   [Archive] [ English ]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 3، شماره 31 - ( زبان: انگليسي- 1388 ) ::
جلد 3 شماره 31 صفحات 118-124 برگشت به فهرست نسخه ها
Effects of Ginger on Spermatogenesis in Streptozotocin-induced Diabetic Rat
چکیده:   (2141 مشاهده)
Background: Ginger rhizome (Zingiber officinale R., family: Zingiberaceae) is used medicinally and as a culinary spice. The medicinal use of ginger dates back to ancient China and India. Objective: Ginger and its constituents are stated to have antiemetic, antithrombotic, antihepatotoxic, anti-inflammatory, stimulant, cholagogue and antioxidant.Enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus. Methods: Wistar male rat (n=40) were allocated into three groups, control group (n=10) and ginger (G) group that received 100mg/kg-perday (oral), (n=10), and Diabetic group that received 55 mg/kg (IP) streptozotocin (STZ) (n=20) which was subdivided to two groups of 10 STZ group and treatment group. Treatment group received 55mg/kg (IP) STZ plus ginger 100mg/kg-perday (G), daily for, 4 weeks, respectively however, the control group just received an equal volume of distilled water daily(IP). Diabetes was induced by a single (IP) injection of streptozotocin (55 mg/kg). Animals were kept in standard condition. In 28day after inducing diabetic 5cc blood were collected for TAC, MDA and sperm parameters and testis tissues of Rat in whole groups were removed then prepared for analyzes. Results:TAC, MDA and sperm parameters significantly decreased in diabetic group.treatment groub that has received Ginger 100 mg/kg (oral) show increasing in TAC and sperm parameters (p<0.05) in comparison to experimental groups (p<0.05). Conclusion: Since in our study 100 mg/kg (oral) ginger have significantly Preventive effect on sperm parameters, so it seems that using it can be effective for treatment in Diabetic Rat.
متن کامل [PDF 135 kb]   (627 دریافت)    
نوع مطالعه: پژوهشي | موضوع مقاله: گياهان دارويي
دریافت: ۱۳۹۳/۸/۷ | پذیرش: ۱۳۹۳/۸/۷ | انتشار: ۱۳۹۳/۸/۷
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

کد امنیتی را در کادر بنویسید >


XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nassiri M, Khaki A, Ahmadi-Ashtiani H, Rezazadeh S, Rastgar H, Gharachurlu S. Effects of Ginger on Spermatogenesis in Streptozotocin-induced Diabetic Rat. JMP. 2009; 3 (31) :118-124
URL: http://jmp.ir/article-1-339-fa.html

Effects of Ginger on Spermatogenesis in Streptozotocin-induced Diabetic Rat. فصلنامه گياهان دارويي. 1388; 3 (31) :118-124

URL: http://jmp.ir/article-1-339-fa.html



دوره 3، شماره 31 - ( زبان: انگليسي- 1388 ) برگشت به فهرست نسخه ها
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
Persian site map - English site map - Created in 0.08 seconds with 31 queries by YEKTAWEB 3638